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Hideto Kawaratani Selected Research

CDAA (Randox)

10/2022Rifaximin and lubiprostone mitigate liver fibrosis development by repairing gut barrier function in diet-induced rat steatohepatitis.
12/2021Angiotensin Receptor Blockers Potentiate the Protective Effect of Branched-Chain Amino Acids on Skeletal Muscle Atrophy in Cirrhotic Rats.
6/2019Exogenous Administration of Low-Dose Lipopolysaccharide Potentiates Liver Fibrosis in a Choline-Deficient l-Amino-Acid-Defined Diet-Induced Murine Steatohepatitis Model.
11/2017Periostin cross‑reacts with the renin‑angiotensin system during liver fibrosis development.
10/2016DNA methylation of angiotensin II receptor gene in nonalcoholic steatohepatitis-related liver fibrosis.
3/2015Reduction of endotoxin attenuates liver fibrosis through suppression of hepatic stellate cell activation and remission of intestinal permeability in a rat non-alcoholic steatohepatitis model.
11/2013Direct renin inhibitor, aliskiren, attenuates the progression of non-alcoholic steatohepatitis in the rat model.
5/2009Losartan, an angiotensin-II type 1 receptor blocker, attenuates the liver fibrosis development of non-alcoholic steatohepatitis in the rat.
11/2008Innate immune reactivity of the liver in rats fed a choline-deficient L-amino-acid-defined diet.

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Hideto Kawaratani Research Topics

Disease

43Liver Cirrhosis (Hepatic Cirrhosis)
10/2022 - 06/2007
38Fibrosis (Cirrhosis)
10/2022 - 12/2008
22Hepatocellular Carcinoma (Hepatoma)
10/2022 - 06/2007
15Fatty Liver
10/2022 - 10/2008
12Neoplasms (Cancer)
01/2021 - 01/2009
11Alcoholic Fatty Liver
10/2022 - 07/2008
11Non-alcoholic Fatty Liver Disease
11/2021 - 11/2009
8Inflammation (Inflammations)
12/2021 - 06/2009
8Insulin Resistance
08/2020 - 01/2009
7Ascites
05/2022 - 02/2017
7Infections
03/2022 - 05/2013
7Liver Diseases (Liver Disease)
10/2021 - 01/2009
6Hepatic Encephalopathy
03/2022 - 12/2017
5Hyperammonemia
08/2022 - 12/2017
5Alcoholic Liver Diseases (Alcoholic Liver Disease)
12/2021 - 04/2011
4Chronic Hepatitis C
10/2022 - 01/2009
4Sarcopenia
08/2022 - 01/2020
4Hemorrhage
01/2021 - 12/2008
4Acute Liver Failure (Fulminant Hepatic Failure)
08/2010 - 08/2008
3Thrombophilia
03/2022 - 05/2019
3Biliary Liver Cirrhosis (Primary Biliary Cirrhosis)
03/2022 - 01/2017
3Dysbiosis
06/2021 - 01/2018
3Muscle Cramp (Cramp)
12/2020 - 01/2019
3Thrombosis (Thrombus)
09/2020 - 12/2008
3Chronic Hepatitis (Chronic Active Hepatitis)
01/2019 - 01/2018
3Hepatitis
09/2017 - 12/2007
2Atrophy
08/2022 - 12/2021
2Pancreatic Neoplasms (Pancreatic Cancer)
05/2022 - 08/2009
2Acute-On-Chronic Liver Failure
04/2022 - 05/2020
2Pleural Effusion (Pleural Effusions)
03/2022 - 08/2017
2Edema (Dropsy)
03/2022 - 02/2018
2Alcoholic Liver Cirrhosis (Alcoholic Cirrhosis)
09/2021 - 07/2021
2Cognitive Dysfunction
06/2021 - 03/2020
2Liver Neoplasms (Liver Cancer)
01/2021 - 01/2018
2Body Weight Changes
01/2021 - 02/2018
2Body Weight (Weight, Body)
01/2021 - 08/2017
2Metabolic Syndrome (Dysmetabolic Syndrome X)
10/2020 - 01/2019

Drug/Important Bio-Agent (IBA)

17EndotoxinsIBA
05/2022 - 06/2009
12Amino AcidsFDA Link
10/2022 - 05/2009
10Choline (Choline Chloride)IBA
10/2022 - 05/2009
10CytokinesIBA
08/2022 - 05/2009
9LipopolysaccharidesIBA
10/2022 - 05/2010
9CDAA (Randox)IBA
10/2022 - 11/2008
9Biomarkers (Surrogate Marker)IBA
04/2022 - 09/2017
8Toll-Like Receptor 4IBA
10/2022 - 08/2008
8von Willebrand FactorIBA
04/2022 - 09/2017
8Losartan (Cozaar)FDA LinkGeneric
01/2022 - 05/2009
7Rifaximin (L 105)FDA Link
10/2022 - 12/2017
7Angiotensin II Type 1 Receptor BlockersIBA
01/2022 - 05/2009
7CollagenIBA
10/2020 - 12/2008
6TolvaptanFDA Link
05/2022 - 02/2017
6Anti-Bacterial Agents (Antibiotics)IBA
12/2021 - 10/2010
6Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
06/2021 - 08/2008
6Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2019 - 08/2009
5Angiotensin IIIBA
12/2021 - 05/2010
5Aspartate Aminotransferases (Aspartate Transaminase)IBA
10/2021 - 09/2017
5DiureticsIBA
01/2021 - 02/2017
5Glucose (Dextrose)FDA LinkGeneric
03/2020 - 11/2017
4Sorafenib (BAY 43-9006)FDA Link
10/2022 - 10/2014
4InterferonsIBA
10/2022 - 01/2009
4AntigensIBA
04/2022 - 09/2017
4EnzymesIBA
04/2022 - 11/2013
4Proteins (Proteins, Gene)FDA Link
03/2022 - 06/2008
4Ursodeoxycholic Acid (Urso)FDA LinkGeneric
01/2022 - 02/2016
4Branched-Chain Amino AcidsIBA
12/2021 - 01/2009
4Angiotensin Receptor AntagonistsIBA
12/2021 - 10/2014
4Carrier Proteins (Binding Protein)IBA
10/2021 - 09/2017
4Therapeutic UsesIBA
12/2020 - 04/2011
4Glutathione Transferase (Glutathione S-Transferase)IBA
06/2018 - 12/2008
4Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
01/2011 - 06/2007
3ZincIBA
03/2022 - 06/2021
3Bile Acids and Salts (Bile Acids)IBA
01/2022 - 11/2017
3Carbon Tetrachloride (Tetrachloromethane)IBA
12/2021 - 01/2021
3Hyaluronic Acid (Hyaluronan)IBA
10/2021 - 08/2020
3Tissue Inhibitor of MetalloproteinasesIBA
10/2021 - 08/2020
3AntioxidantsIBA
06/2021 - 12/2020
3Messenger RNA (mRNA)IBA
01/2021 - 08/2008
3Alanine Transaminase (SGPT)IBA
04/2020 - 09/2017
3AldosteroneIBA
08/2017 - 05/2010
3Pharmaceutical PreparationsIBA
03/2014 - 06/2007
2MyostatinIBA
08/2022 - 03/2022
2SteroidsIBA
03/2022 - 10/2008
2AmmoniaIBA
03/2022 - 03/2020
2Ethanol (Ethyl Alcohol)IBA
12/2021 - 01/2021
2AlbuminsIBA
10/2021 - 09/2019
2Collagen Type III (Type III Collagen)IBA
10/2021 - 08/2020
2Triglycerides (Triacylglycerol)IBA
09/2021 - 06/2020
2InterleukinsIBA
06/2021 - 09/2017
2Interleukin-8 (Interleukin 8)IBA
06/2021 - 09/2017
2AnticoagulantsIBA
01/2021 - 09/2020
2lenvatinibIBA
01/2021 - 01/2021
2Reactive Oxygen Species (Oxygen Radicals)IBA
01/2021 - 07/2008
2Carnitine (L-Carnitine)FDA LinkGeneric
12/2020 - 01/2019
2procollagen Type III-N-terminal peptide (PIIP)IBA
10/2020 - 08/2020

Therapy/Procedure

19Therapeutics
05/2022 - 06/2008
7Oral Administration
10/2022 - 01/2018
6Drug Therapy (Chemotherapy)
12/2020 - 01/2015
3Intraperitoneal Injections
01/2021 - 01/2019
2Liver Transplantation
06/2021 - 01/2018
2Blood Transfusion (Blood Transfusions)
01/2021 - 01/2017